Repolarization Stratification for Dipole Electrocardiotopography
نویسندگان
چکیده
The dipole component of the heart electric field has been analyzed in the context of distribution of the action potential onset timing and its duration. It has been demonstrated that the process of repolarization can be visualized as a sequence of layers with equal action potential (AP) completion time. Dipole moments of these layers can be calculated from the repolarization part of VCG and visualized as by dipole electrocardiography method (DECARTO) with the use of simple biophysical models. Such presentation will be useful for the analysis of heterogeneity of action potential characteristics in the ventricular myocardium and evaluation of its vulnerability to life-threatening arrhythmias.
منابع مشابه
Recognition of right ventricular hypertrophy using the DECARTO images of the cardioelectric characteristics
There are presented results of experimental-laboratory testing a new method to diagnose the right ventricular hypertrophy. The method is based upon the dipole electrocardiotopography (DECARTO) technique, proposed formerly by the authors and successfully applied for recognition of the left ventricular hypertrophy. The results obtained on reliably verified groups of normal and diseased persons sh...
متن کاملModelling and imaging cardiac repolarization abnormalities.
Repolarization abnormalities, including those induced by the congenital or acquired long QT (LQT) syndrome, provide a substrate for life-threatening cardiac arrhythmias. In this article, we use computational biology to link HERG mutations mechanistically to the resulting abnormalities of the whole-cell action potential. We study how the kinetic properties of I(Ks) (the slow delayed rectifier) t...
متن کاملNoninvasive assessment of local myocardium repolarization changes using high resolution surface ECG mapping.
A method using body surface potential maps for assessment of myocardium lesions with changed repolarization is presented and suitable mapping system is introduced. Differences between normal and altered QRST integral maps together with torso volume conductor model were used to determine the equivalent dipole representing the lesion. Performance of the method was studied on simulated data. Chang...
متن کاملCardiac repolarization analysis using the surface electrocardiogram.
Sudden cardiac death (SCD) is a challenging health problem in the western world. Analysis of cardiac repolarization from the electrocardiogram (ECG) provides valuable information for stratifying patients according to their risk of suffering from arrhythmic events that could end in SCD, as well as for assessing efficacy of antiarrhythmic therapies. In this paper, we start by exploring the cellul...
متن کاملRisk stratification of patients with early repolarization…still an unresolved matter!
The study by Stavrakis S et al. “Development and Validation of a Prognostic Index for Risk Stratification of Patients with Early Repolarization”1 proposes a risk stratification model for patients with early repolarization (defined as J-point elevation ≥0.1 mV in inferior/lateral leads). Their model, including the parameters older age, lower body mass index, non-African American race, current us...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2013